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Acute Myelogenous Leukemia

Recent findings in acute myelogenous leukemia in children described by researchers from Hokkaido University, Department of Pediatrics

Published in Disease Risk Factor Week, April 15th, 2007

New research, "Extramedullary infiltration at diagnosis and prognosis in children with acute myelogenous leukemia," is the subject of a report. "Extramedullary infiltration (EMI) is an occasional clinical symptom in childhood acute myelogenous leukemia (AML), but there is considerable controversy regarding the prognostic significance of EMI in AML. PROCEDURE: We evaluated the frequency and prognostic significance of EMI at diagnosis of AML in children," researchers in Sapporo, Japan report.

"Of 240 cases of de novo AML excluding children with Down syndrome and acute promyelocytic leukemia, 56 (23.3%) showed EMI at diagnosis. Patients with EMI had a higher initial WBC...

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