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Alcoholism Risk Factors

Researchers from Tohoku University, Division of Gastroenterology detail new studies and findings in the area of alcoholism risk factors

Published in Disease Risk Factor Week, April 15th, 2007

Researchers detail in "Differential roles of the SPINK1 gene mutations in alcoholic and nonalcoholic chronic pancreatitis," new data in alcoholism. "Risk factors for chronic pancreatitis (CP) are largely unknown except for alcohol. Identification of environmental and genetic risk factors is important for the early diagnosis of CP," researchers in Sendai, Japan report.

"We here examined the prevalence of the serine protease inhibitor Kazal type 1 (SPINK1) gene mutations in Japanese patients with CP, and whether the disease course was different between mutation-positive and -negative patients. Genomic DNA was prepared from 96 CP patients and 165 healthy controls. All...

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