Metaplasia
New metaplasia research from Erasmus University described
Published in Disease Risk Factor Week, December 23rd, 2007
"Background and study aims: In patients with presumed Barrett esophagus we evaluated clinical risk factors that could predict the presence of intestinal metaplasia and dysplasia in biopsies of columnar-lined esophagus (CLE), independently of histological results. In 908 patients with CLE of length ! 2 cm, data on age, sex, reflux symptoms, tobacco and alcohol use, medication use, and upper gastrointestinal endoscopy findings were prospectively collected," scientists in Netherlands report.
"Multivariate logistic regression analysis was performed, and a model for predicting the histological results was developed. In 127/908 patients, biopsies of CLE did not contain...
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