Von Willebrand Disease

Data on von Willebrand disease reported by M. Dinisio and co-researchers

Published in Disease Risk Factor Week, December 23rd, 2007

According to recent research from Chieti, Italy, "Toll-like receptor-4 (TLR-4) gene polymorphisms have been associated with a lower risk of atherosclerosis. High levels of soluble P-selectin (sP-selectin) and von Willebrand factor predict an increased risk for cardiovascular events and correlate to atherosclerotic risk factors."

"The relationship between these markers and TLR-4 gene polymorphisms was evaluated in a cohort of consecutive hypercholesterolemic outpatients. TLR-4 gene polymorphisms were detected in 48 out of 330 (14%) patients with hypercholesterolemia. Lipid and inflammatory markers, sP-selectin and von Willebrand were evaluated in carriers and in 96...

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Source: Disease Risk Factor Week (2007-12-23)

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