Alzheimer Disease
Studies from University of Cantabria in the area of Alzheimer disease published
Published in Disease Risk Factor Week, January 13th, 2008
According to a study from Santander, Spain, "As transforming growth factor-beta 1 (TGF-beta 1) determines important neurotrophic and neuroprotective actions, we postulated serum TGF-beta 1 levels could be low in Alzheimer's disease (AD), and TGF-beta 1 genetic variation could be associated with AD risk through modulating serum TGF-beta 1 levels. TGF-beta 1 (-800) (rs 1800468), (-509) (rs 1800469) and (+869) (rs 1982073) polymorphisms were genotyped in 412 AD patients and 406 controls."
"We measured serum TGF-beta 1 levels (by ELISA) in 63 AD patients and compared them with 77 age- and gender-matched non-demented controls. Serum TGF-beta 1 levels were not different in AD...
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