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Cardiovascular Disease

Maltreatment during childhood associated with combination of inflammation and depression in adults

Published in Disease Risk Factor Week, April 27th, 2008

A history of neglect or abuse in childhood appears to be associated with depression and inflammation in adulthood, a combination that may increase cardiovascular risk, according to a report in the April issue of Archives of General Psychiatry, one of the JAMA/Archives journals.

"Major depression is a multisystemic disorder that affects both brain and bodily functions," the authors write as background information in the article. Depression and cardiovascular disease often occur simultaneously, and inflammation (chronic activation of the immune system) has been linked to both. "However, not all individuals with depression have elevated levels of inflammation. Those who do...

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