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Clinical Trial Research

New clinical trial research study findings have been published by scientists at Leiden University

Published in Disease Risk Factor Week, January 11th, 2009

According to recent research published in the American Journal of Epidemiology, "Multiple control groups in case-control studies are used to control for different sources of confounding. For example, cases can be contrasted with matched controls to adjust for multiple genetic or unknown lifestyle factors and simultaneously contrasted with an unmatched population-based control group."

"Inclusion of different control groups for a single exposure analysis yields several estimates of the odds ratio, all using only part of the data. Here the authors introduce an easy way to combine odds ratios from several case-control analyses with the same cases. The approach is...

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