Alzheimer Disease Therapy
Studies from University of California, Department of Medicine provide new data on Alzheimer disease therapy
Published in Disease Risk Factor Week, February 8th, 2009
Data detailed in 'Use of copper and insulin-resistance to accelerate cognitive deficits and synaptic protein loss in a rat Abeta-infusion Alzheimer's disease model' have been presented. "The rat amyloid-beta (Abeta) intracerebroventricular infusion can model aspects of Alzheimer's disease (AD) and has predicted efficacy of therapies such as ibuprofen and curcumin in transgenic mouse models. High density lipoprotein (HDL), a normal plasma carrier of Abeta, is used to attenuate Abeta aggregation within the pump, causing Abeta-dependent toxicity and cognitive deficits within 3 months," scientists writing in the Journal of Alzheimer's Disease report.
"Our goal was to...
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