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Alzheimer Disease

New findings from R. Squitti and co-researchers in the area of Alzheimer disease described

Published in Disease Risk Factor Week, February 22nd, 2009

According to recent research published in the journal Neurology, "Serum copper not bound to ceruloplasmin (''free'') appears slightly elevated in patients with Alzheimer disease ( AD). We explored whether a deregulation of the free copper pool can predict AD clinical worsening."

"We assessed levels of copper, iron, zinc, transferrin, ceruloplasmin, peroxides, total antioxidant capacity, free copper, and apolipoprotein E genotype in 81 patients with mild or moderate AD, mean age 74.4, SD = 7.4 years, clinically followed up after 1 year. The association among biologic variables under study and Mini-Mental State Examination (MMSE) ( primary outcome), activities of...

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