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Hypertension

New hypertension study findings have been published by V.F. Panoulas and colleagues

Published in Disease Risk Factor Week, March 8th, 2009

According to a study from Dudley, the United Kingdom, "Part of the deleterious effects of systemic inflammation on the cardiovascular system of patients with RA may be exerted via increased propensity to hypertension. IL-6 and TGF-1 are important regulators of the inflammatory response."

"In some, but not all, studies, IL6 174G/C (rs1800795) and TGFB1 869T/C (rs1982073) gene polymorphisms have been associated with hypertension in the general population. The present study addressed their potential association with hypertension in RA patients. TGFB1 869T/C and IL6 174G/C were identified in 400 RA patients and 422 local, non-RA controls using real-time PCR and melting...

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