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Acid Reflux Disease Gene Therapy

New research on acid reflux disease gene therapy from Brown University summarized

Published in Disease Risk Factor Week, February 28th, 2010

Data detailed in 'Bile acid reflux contributes to development of esophageal adenocarcinoma via activation of phosphatidylinositol-specific phospholipase Cgamma2 and NADPH oxidase NOX5-S' have been presented. According to recent research published in the journal Cancer Research, "Gastroesophageal reflux disease complicated by Barrett's esophagus (BE) is a major risk factor for esophageal adenocarcinoma (EA). However, the mechanisms of the progression from BE to EA are not fully understood."

"Besides acid reflux, bile acid reflux may also play an important role in the progression from BE to EA. In this study, we examined the role of phosphatidylinositol-specific...

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