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Daclizumab shows potential for new immunoregulatory approach to treating MS

Published in Disease Risk Factor Week, March 7th, 2010

Biogen Idec (NASDAQ: BIIB) and Facet Biotech Corporation (NASDAQ: FACT) announced the publication of Phase 2 data showing that the addition of daclizumab to interferon beta (IFN(beta)) led to a significant reduction in the number of new or enlarged multiple sclerosis (MS) lesions when compared to IFN(beta) alone in patients with active relapsing forms of MS. The trial, called CHOICE, also showed that daclizumab led to an increase in a subset of the natural killer (NK) cells that help regulate the immune system. These data were published in Online First, the online edition of The Lancet Neurology, and will be published in the April issue of the Lancet Neurology.

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