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Carcinogenesis

Researchers from University of Basque Country, Department of Stomatology publish new studies and findings in the area of carcinogenesis

Published in Disease Risk Factor Week, March 7th, 2010

New research, 'Oral cancer and polymorphism of ethanol metabolising genes,' is the subject of a report. According to recent research from Spain, "Oral cancer is the sixth most common cancer worldwide and a major health problem in some parts of the world. Epidemiological studies have shown that habitual alcohol consumption could be a risk factor in oral carcinogenesis, although the true involvement of alcohol is unknown."

"Via alcohol dehydrogenase (ADH) and cytochrome P450 oxidase (CYP) alcohol is metabolized to acetaldehyde, a highly toxic compound, which plays an important role in carcinogenesis. Subsequently, and during the metabolizing process, acetaldehyde becomes...

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