University of Mediterranee, Marseille
Multispacer typing useful for strain genotyping during outbreaks/bioterrorism
Published in Drug Law Weekly, March 22nd, 2005
According to a study from France, "By use of the nearly perfectly colinear genomes of Rickettsia conorii and Rickettsia prowazekii, we compared the usefulness of three types of sequences for typing of R. conorii isolates: (1) 5 variable coding genes comprising the 16S ribosomal DNA, gltA, ompB, and sca4 (gene D) genes, which are present in both genomes, and the ompA gene, which is degraded in R. prowazekii; (2) 28 genes degraded in R. conorii but intact in R. prowazekii, including 23 split and 5 remnant genes; and (3) 27 conserved and 25 variable...
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Source: Drug Law Weekly (2005-03-22)
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