Published in Drug Law Weekly, August 16th, 2005
"The pathophysiology of anaphylactic shock during anesthesia is incompletely characterized," anesthesiologists in France noted. "It is described as distributive by analogy with septic shock (anaerobic metabolism, high tissue oxygen pressure (PtiO2 ) values)," but the "PtiO2 profile and its metabolic consequences during anaphylaxis are not known."
In a study conducted by P. Dewachter and coauthors at CHU Nancy, "ovalbumin-sensitized anaphylactic shock rats (n=11) were compared to nicardipine-induced hypotension rats...
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Source: Drug Law Weekly (2005-08-16)
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