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Beaumont Hospital, Dublin, Ireland
Researchers from Beaumont Hospital describe findings in cancer
November 7th, 2006
A new study, "Oncological implications of hypoxia inducible factor-1alpha (HIF-1alpha) expression," is now available. "Solid tumours contain regions of hypoxia, which may be a prognostic indicator and determinant of malignant progression, metastatic development and chemoradio-resistance. The degree of intra-tumoural hypoxia has been shown to be positively correlated with the expression of the transcription factor hypoxia-inducible factor 1," scientists in Dublin, Ireland report. "HIF-1 is composed of 2 sub-units, namely HIF-1alpha and HIF-1beta. The production of hypoxia inducible factor 1-alpha has been identified as a key element in allowing cells to adapt and survive...
Source: Drug Law Weekly (2006-11-07)
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