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American Thoracic Society, U.S.



Antioxidant levels may represent treatment focus for silicosis



November 7th, 2006

Levels of heme oxygenase-1 (HO-1), an antioxidant that protects against reactive oxygen species (damaging oxygen molecules that cause direct tissue injury), become elevated in the lungs of chronic silicosis patients and could represent a new treatment approach for the disease.

These results appear in a recent issue of the American Journal of Respiratory and Critical Care Medicine, published by the American Thoracic Society.

Yoshiaki Ishigatsubo, MD, PhD, of the Department of Internal Medicine and Clinical Immunology at Yokohama City University in Japan, and 11 associates studied 46 male patients with silicosis, an inflammatory disorder caused...


Source: Drug Law Weekly (2006-11-07)

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