Diabetic Neuropathy

Avanir publishes phase II diabetic neuropathic pain trial results

Published in Drug Law Weekly, November 14th, 2006

Avanir Pharmaceuticals (AVNR) announced that results of a phase II clinical trial evaluating escalating doses of Neurodex in the treatment of painful diabetic neuropathy were published for the first time in Clinical Therapeutics (Vol 28, Number 10, 2006).

The published article "Dextromethorphan and Quinidine in Adult Patients with Uncontrolled Painful Diabetic Peripheral Neuropathy: A 29-Day, Multicenter, Open-Label, Dose-Escalation Study" indicates that the investigational new drug was well tolerated up to the highest target dose (60 mg dextromethorphan and 60 mg of quinidine dosed twice per day).

The open label trial, conducted at five U.S....

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Source: Drug Law Weekly (2006-11-14)

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