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Neuroscience

Findings in neuroscience reported from Shanghai Jiao Tong University

Published in Drug Law Weekly, November 28th, 2006

Data detailed in "Hippocampus protein profiling reveals aberration of malate dehydrogenase in chlorpromazine/clozapine treated rats" have been presented. According to recent research from Shanghai, People's Republic of China, "Chlorpromazine and clozapine are antipsychotic agents used to relieve symptoms of early-diagnosed schizophrenia. In this study, we used proteomics technology to screen the protein aberration in Sprague-Dawley rats treated with these two antipsychotic agents."

"Our goal was to identify the effects of antipsychotics on hippocampal proteins in rats. Protein expression profiles were compared in each experimental group using two-dimensional gel...

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