Hormones
Researchers at Chungbuk National University, Institute of Veterinary Medicine publish new data on hormones
Published in Drug Law Weekly, December 19th, 2006
Current study results from the report, "Anti-progestogenic effect of flutamide on uterine expression of calbindin-D9k mRNA and protein in immature mice," have been published. According to recent research from Korea, "A calcium binding protein, calbindin-D9k (CaBP-9k), is a cytosolic protein and regulated by steroid hormones in the reproductive tissues. Mouse CaBP-9k gene was predominantly regulated by progesterone (P4), whereas rat CaBP-9k was mainly regulated by 17beta-estradiol (E2) in the uterus."
"The induction of CaBP-9k can be employed as a biomarker for steroidal substrates as endocrine disruptors (EDs). Flutamide (FLU) is a non-steroidal anti-androgen or...
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Source: Drug Law Weekly (2006-12-19)
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