Ureteral Obstruction Therapy
Study results from Eulji Hospital, Division of Nephrology broaden understanding of ureteral obstruction therapy
Published in Drug Law Weekly, January 16th, 2007
Researchers detail in "Reduction of renal fibrosis as a result of liposome encapsulated clodronate induced macrophage depletion after unilateral ureteral obstruction in rats," new data in ureteral obstruction. According to a study from Seoul, Korea, "Macrophages have been thought to play a role in renal tubulointerstitial fibrosis; recent reports have demonstrated an antifibrotic effect of macrophages in late-stage renal fibrosis. Liposome-encapsulated clodronate (LC) produces a selective and systemic depletion of phagocytic macrophages in vivo."
"To study the role of initial infiltrating macrophages in renal fibrosis, we compared the effects of pretreatment with LC and...
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Source: Drug Law Weekly (2007-01-16)
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