Bacteriology

Scientists use peptides and lipopeptides to fight bacteria

Published in Drug Law Weekly, January 16th, 2007

By combining key properties of two different types of weapons used by the innate defense systems of organisms, a team of scientists at the Weizmann Institute of Science has managed to design a more powerful weapon, hoping that this will provide a basis for novel and more effective antibiotics.

The first is a "magnetic" weapon - a natural antibiotic produced by all organisms. Because these antimicrobial peptides (AMPs) are positively charged, they are attracted to the bacteria's negatively charged surface like a magnet, where they can then exert their antibacterial effects. The second, "detergent-like" weapon - called a lipopeptide - is produced only by bacteria and...

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Source: Drug Law Weekly (2007-01-16)

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