Drug Delivery
Study results from National University of Singapore, Department of Biochemistry in the area of drug delivery published
Published in Drug Law Weekly, January 16th, 2007
New research, "Intracellular drug delivery by sulfatide-mediated liposomes to gliomas," is the subject of a report. According to recent research from Singapore, Singapore, "We described here a liposomal carrier system in which the targeting ligand was sulfatide, a glycosphingolipid known to bind several extracellular matrix (ECM) glycoproteins whose expression was highly up-regulated in many tumors. In vitro experiments with human glioma cell lines demonstrated that robust intracellular uptake of the liposomes depended specifically on the presence of sulfatide as the key liposomal component."
"Significant amount of the liposomes remained largely intact in the cytoplasm...
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Source: Drug Law Weekly (2007-01-16)
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