Life Sciences Therapy
New life sciences therapy study results reported from University of Wurzburg, DFG Research Center for Experimental Biomedicine
Published in Drug Law Weekly, February 20th, 2007
Data detailed in "Real-time optical recording of beta1-adrenergic receptor activation reveals supersensitivity of the Arg389 variant to carvedilol" have been presented. "Antagonists of beta-adrenergic receptors (beta-ARs) have become a main therapeutic regimen for the treatment of heart failure even though the mechanisms of their beneficial effects are still poorly understood. Here, we used fluorescent resonance energy transfer-based (FRET-based) approaches to directly monitor activation of the beta(1)-AR and downstream signaling," scientists in Wurzburg, Germany report.
"While the commonly used beta-AR antagonists metoprolol, bisoprolol, and carvedilol displayed...
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Source: Drug Law Weekly (2007-02-20)
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