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Anesthesiology
Research on anesthesiology described by scientists at University of Kentucky, Department of Anesthesiology
April 10th, 2007
A new study, "Characterization of the antinociceptive and pronociceptive effects of methadone in rats," is now available. "Recently, it has been appreciated that in addition to their antinociceptive properties, opioid analgesics also can enhance pain sensitivity (opioid-induced hyperalgesia [OIH]). OIH may enhance preexisting pain and contribute to dose escalation, tolerance, and misuse/abuse of opioids," scientists in the United States report. "Better information is needed to determine which opioid or opioid combinations may be least likely to produce OIH and therefore possibly represent better choices for pain management. Herein the authors have examined the...
Source: Drug Law Weekly (2007-04-10)
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