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Anesthesiology
Research on anesthesiology reported by scientists at National Cheng-Kung University
April 10th, 2007
A report, "High-dose morphine impairs vascular endothelial function by increased production of superoxide anions," is newly published data in Anesthesiology. According to recent research from Taiwan, "The effects of high-dose morphine on vascular endothelial function have not been previously shown. The authors hypothesized that the pro-oxidant effect of high-dose morphine impairs vascular endothelial function." "Mice were subjected to placebo or morphine (20 mg/kg intraperitoneal) injection for consecutive 14 days. Aortas were harvested for assessment of vasomotor function by isometric force recordings. Protein expression p47phox was determined by Western...
Source: Drug Law Weekly (2007-04-10)
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