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Drug Law Weekly

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Angiogenesis



Reports summarize angiogenesis research from National Cancer Center, Division of Medical Sciences



April 10th, 2007

New research, "Enhancement of glioblastoma radioresponse by a selective COX-2 inhibitor celecoxib: inhibition of tumor angiogenesis with extensive tumor necrosis," is the subject of a report. In this recent report, researchers in Singapore, Singapore conducted a study "Toward improved glioblastoma multiforme treatment, we determined whether celecoxib, a selective cyclooxygenase (COX)-2 inhibitor, could enhance glioblastoma radiosensitivity by inducing tumor necrosis and inhibiting tumor angiogenesis. U-87MG cells treated with celecoxib, irradiation, or both were assayed for clonogenic survival and angiogenic factor protein analysis (angiopoietin-1, angiopoietin-2, and vascular endothelial...


Source: Drug Law Weekly (2007-04-10)

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