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Drug Law Weekly

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Angiogenesis



Studies from Harvard University, Department of Radiation Oncology yield new information about angiogenesis



April 10th, 2007

Investigators publish new data in the report "Effect of vascular normalization by antiangiogenic therapy on interstitial hypertension, peritumor edema, and lymphatic metastasis: insights from a mathematical model." According to recent research published in the journal Cancer Research, "Preclinical and clinical evidence shows that antiangiogenic agents can decrease tumor vessel permeability and interstitial fluid pressure (IFP) in a process of vessel "normalization." The resulting normalized vasculature has more efficient perfusion, but little is known about how tumor IFP and interstitial fluid velocity (IFV) are affected by changes in transport properties of the vessels and...


Source: Drug Law Weekly (2007-04-10)

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