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Drug Law Weekly

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Angiology



Research in the area of angiology reported from University of Nottingham, Center for Integrated Systems Biology and Medicine



April 10th, 2007

Scientists discuss in "Evidence that a prostanoid produced by cyclo-oxygenase-2 enhances contractile responses of the porcine isolated coronary artery following exposure to lipopolysaccharide" new findings in angiology. "Prolonged incubation of porcine isolated coronary artery (PCA) to lipopolysaccharide (LPS) causes a moderate reduction in vessel constrictive responsiveness. This has been attributed mainly to the induction of nitric oxide synthase (NOS)," researchers in Nottingham, the United Kingdom report.

"We aimed to investigate the role of induction of cyclo-oxygenase (COX) and expression of endothelin receptor 1-A (ET1(A)) in modulating the vascular responses of...


Source: Drug Law Weekly (2007-04-10)

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