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OctoPlus obtains full rights to PolyActive drug delivery technology from IsoTis

Published in Drug Law Weekly, May 8th, 2007

OctoPlus N.V. ("OctoPlus" or the "Company") (Euronext: OCTO), the drug delivery and development company, announces today that it reached agreement with IsoTis, Inc. (NASDAQ: ISOT) to obtain additional rights to its PolyActive(tm) drug delivery technology, the technology used in OctoPlus' lead product Locteron(tm). Locteron is a controlled release formulation of interferon alfa for the treatment of chronic hepatitis C, currently in Phase IIa studies.

Under the revised agreement, OctoPlus obtains full rights to the PolyActive technology and its intellectual property in certain strategic areas, including additional applications in orthopedics. Furthermore, the contract...

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