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Drug Law Weekly

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Allergies Therapy



Mount Sinai School of Medicine describes research in allergies therapy



June 26th, 2007

Current study results from the report, "Mutational analysis of immunoglobulin E-binding epitopes of beta-casein and beta-lactoglobulin showed a heterogeneous pattern of critical amino acids between individual patients and pooled sera," have been published. According to a study from the United States, "For immunotherapeutic approaches, 'critical' amino acids (AAs) within allergenic epitopes are replaced with alternate AAs to eliminate IgE antibody binding. To determine the critical AAs for IgE binding in beta-casein and beta-lactoglobulin (BLG)."

"Peptides of 10-14 AAs in length were synthesized on a derivatized cellulose membrane with single AA substitutions (alanine or...


Source: Drug Law Weekly (2007-06-26)

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