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Drug Law Weekly

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Alzheimer Disease



Research in the area of Alzheimer disease reported from Helsinki University



June 26th, 2007

Researchers detail in "Effects of NMDA receptor antagonist memantine on mismatch negativity," new data in Alzheimer disease. "Mismatch negativity (MMN) and its magnetic counterpart (MMNm) have been shown to be altered in patients with various psychiatric and neurological disorders, e.g. Alzheimer's disease and schizophrenia, indicating deficits in involuntary attention," scientists writing in the journal Brain Research Bulletin report.

"N-Methyl-D-aspartate (NMDA) receptor-mediated glutamate dysfunction is suggested to underlie these deficits. However, the role of NMDA receptors in involuntary attention is poorly understood. Memantine is an NMDA receptor...


Source: Drug Law Weekly (2007-06-26)

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