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Drug Law Weekly

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Analgesics



Research from University of Wales, Wales College of Medicine in the area of analgesics described



June 26th, 2007

Investigators publish new data in the report "Comparison of the analgesic efficacy and respiratory effects of morphine, tramadol and codeine after craniotomy. Pain after craniotomy remains a significant problem. The effect of morphine and tramadol patient-controlled analgesia (PCA) on arterial carbon dioxide tension is unknown in patients having such surgery," researchers in Cardiff, the United Kingdom report.

"Sixty craniotomy patients were randomly allocated to receive morphine PCA, tramadol PCA or codeine phosphate 60 mg intramuscularly. Baseline values of pain score (0-10), sedation and arterial carbon dioxide tension were recorded at the time of first analgesic...


Source: Drug Law Weekly (2007-06-26)

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