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Cardiology

Scientists at Annamalai University, Department of Biochemistry describe research in cardiology

Published in Drug Law Weekly, July 10th, 2007

Research findings, "Effect of leptin on peroxidation and antioxidant defense in ethanol-supplemented Mus musculus heart," are discussed in a new report. "The aim of the study was to evaluate the effect of exogenous mouse leptin on ethanol-induced cardiac toxicity in mice. Administering ethanol (6.32 g/kg body weight p.o.) to 4-week-old healthy mice for 45 days resulted in significantly elevated plasma levels of leptin, lactate dehydrogenase (LDH), cardiac lipid hydroperoxides (LOOH) and thiobarbituric acid reactive substances (TBARS) and significantly decreased cardiac superoxide dismutase, catalase, vitamin C, vitamin E, reduced glutathione and glutathione-dependent enzyme levels...

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