Drug Resistance
Scientists at Fudan University, Department of Pharmaceutics detail research in drug resistance
Published in Drug Law Weekly, July 10th, 2007
A new study, "Difunctional Pluronic copolymer micelles for paclitaxel delivery: synergistic effect of folate-mediated targeting and Pluronic-mediated overcoming multidrug resistance in tumor cell lines," is now available. According to recent research published in the International Journal of Pharmaceutics, "A significant obstacle for successful chemotherapy with paclitaxel (PTX) is multidrug resistance (MDR) in tumor cells. Micelles and mixed micelles were prepared from Pluronic block copolymer P105 or L101 as PTX delivery systems for overcoming MDR."
"Both micelle systems were covalently modified with the targeting agent folic acid to recognize and bind a...
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Source: Drug Law Weekly (2007-07-10)
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