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Drug Law Weekly

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Anesthesia



Findings from Alfred Hospital in anesthesia reported



July 10th, 2007

Investigators publish new data in the report "Accuracy of dilution of morphine for intrathecal use." According to a study from Melbourne, Australia, "Morphine is administered intrathecally alone or in combination with other drugs to provide spinal analgesia. Dose-finding studies have recommended 100 microg be used intrathecally to optimise analgesia and minimise side-effects for caesarean section and hip replacement surgery."

"Dilute solutions of morphine are generally not available, mandating preparation from a 10 mg/ml ampoule. We postulated that diluting morphine would be inaccurate and imprecise, contributing to the variability in patient response often reported....


Source: Drug Law Weekly (2007-07-10)

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