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Anesthesia
New anesthesia study findings have been reported by scientists at Gyeongsang National University
July 10th, 2007
Researchers detail in "Inhibitory effect of tramadol on vasorelaxation mediated by ATP-sensitive K+ channels in rat aorta," new data in anesthesia. According to recent research from Korea, "Tramadol produces a conduction block similar to lidocaine by exerting a local anesthetic-like effect. The aims of this in vitro study were to determine the effects of tramadol on the vasorelaxant response induced by the adenosine triphosphate-sensitive K(+) (K(ATP)) channel opener, levcromakalim, in an endothelium-denuded rat aorta, and to determine whether this effect of tramadol is stereoselective." "The effects of tramadol (racemic, R(-) and S(+): 10(-6), 10(-5), 5 x 10(-5) M),...
Source: Drug Law Weekly (2007-07-10)
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