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Drug Law Weekly

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Angiogenesis



Research on angiogenesis published by scientists at University of Pittsburgh, Pittsburgh Cancer Institute



July 10th, 2007

Fresh data on angiogenesis are presented in the report "Endostatin plus interferon-alpha2b therapy for metastatic melanoma: a novel combination of antiangiogenic and immunomodulatory agents." According to a study from the United States, "In patients with stage IIB-III disease, adjuvant high-dose interferon-alpha2b has shown clinical benefit, although metastatic melanoma is currently without any known survival-prolonging therapy. Angiogenesis has been considered important in melanoma progression, and endostatin is an angiogenesis inhibitor with antitumor activity that has shown promising results in murine model systems, prompting investigation of a formulation of rh-Endostatin (EntreMed,...


Source: Drug Law Weekly (2007-07-10)

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