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Drug Law Weekly

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Angiology



Research on angiology published by scientists at University of Sao Paulo



July 10th, 2007

New investigation results, "Effect of chronic ethanol consumption on endothelin-1 generation and conversion of exogenous big-endothelin-1 by the rat carotid artery," are detailed in a study published in Alcohol. According to recent research published in the journal Alcohol, "The purpose of the present work was to investigate whether conversion of exogenous applied big-endothelin-1 (Big-ET-1) as well as the basal release and mRNA levels of endothelin-1 (ET-1) is altered by ethanol consumption in the rat carotid. The measurement of the contraction induced by Big-ET-1 served as an indicative of functional endothelin (ET)-converting enzyme (ECE) activity."

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Source: Drug Law Weekly (2007-07-10)

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