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Myeloma Prevention

New myeloma prevention research has been reported by scientists at General Airforce Hospital

Published in Drug Law Weekly, August 28th, 2007

Fresh data on myeloma are presented in the report "Myeloma bone disease and proteasome inhibition therapies. Bone disease is one of the most debilitating manifestations of multiple myeloma. A complex interdependence exists between myeloma bone disease and tumor growth, creating a vicious circle of extensive bone destruction and myeloma progression," investigators in Athens, Greece report.

"Proteasome inhibitors have recently been shown to promote bone formation in vitro and in vivo. Preclinical studies have demonstrated that proteasome inhibitors, including bortezomib, which is the first-in-class such agent, stimulate osteoblast differentiation while inhibiting...

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