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Enteritis Physiology

Research from Royal Adelaide Hospital provides new data about enteritis physiology

Published in Drug Law Weekly, August 28th, 2007

Research findings, "Roles of muscarinic receptor subtypes in small intestinal motor dysfunction in acute radiation enteritis," are discussed in a new report. According to recent research from Adelaide, Australia, "Administration of abdominal radiotherapy results in small intestinal motor dysfunction. We have developed a rat radiation enteritis model that, after exposure in vivo, shows high-amplitude, long-duration (HALD) pressure waves in ex vivo ileal segments."

"These resemble in vivo dysmotility where giant contractions migrate both antegradely and retrogradely. Mediation of these motor patterns is unclear, although enteric neural components are implicated. After the...

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