Biopharmaceuticals
Research reports from University of Helsinki provide new insights into biopharmaceuticals
Published in Drug Law Weekly, September 4th, 2007
Scientists discuss in "Phase transformations of erythromycin A dihydrate during pelletisation and drying" new findings in biopharmaceuticals. According to recent research from Helsinki, Finland, "An at-line process analytical approach was applied to better understand process-induced transformations of erythromycin dihydrate during pellet manufacture (extrusion-spheronisation and drying process). The pellets contained 50% (w/w) erythromycin dihydrate and 50% (w/w) microcrystalline cellulose, with purified water used as a granulating fluid."
"To characterise changes in solid-state properties during processing, near infrared (NIR) spectroscopy and X-ray powder diffraction...
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Source: Drug Law Weekly (2007-09-04)
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