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Cell Biology

Studies from University of Ferrara have provided new information about cell biology

Published in Drug Law Weekly, October 2nd, 2007

A new study, "Cisplatin cytotoxicity in organ of corti-derived immortalized cells," is now available. According to a study from Ferrara, Italy, "Cisplatin is an anticancer drug currently used in the treatment of genital and head and neck tumors. Its use in these and other types of tumors is narrowed by onset of chemoresistance and severe undesired side effects, like as nephro-and ototoxicity, whose mechanisms of action are only partially understood."

"In the present study we investigated the effects of cisplatin (cis-dichlorodiaminoplatin, CDDP) on a cell line (OC-k3) developed from organs of Corti of transgenic mice. We observed at 48 h that cell death due to cisplatin...

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