Published in Drug Law Weekly, October 9th, 2007
"Simultaneous administration Of P-4 together with E-2 blocked this effect. Pharmacological inhibition of GSK-3 beta activity in mice treated with P4E2 reversed the nuclear exclusion of cyclin D2 in the uterine epithelial cells and this caused phosphorylation of Rb protein and progression of cells towards S-phase," wrote Y. Wang and colleagues, Fudan University.
The researchers concluded: "Our results indicate that GSK-3 beta...
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