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Asthma Therapy

Researchers from University of Nottingham, Division of Respiratory Medicine publish new studies and findings in the area of asthma therapy

Published in Drug Law Weekly, October 30th, 2007

Research findings, 'Plasma concentrations of fluticasone propionate and budesonide following inhalation: effect of induced bronchoconstriction,' are discussed in a new report. According to a study from the United Kingdom, "'AIMS: To determine whether and to what extent bronchoconstriction affects plasma concentrations of fluticasone and budesonide following inhalation. Twenty people with mild asthma inhaled 1000 microg fluticasone (Accuhaler) plus 800 microg budesonide (Turbohaler) on two visits."

"On one occasion, prior to drug inhalation, FEV(1) was decreased by at least 25% using inhaled methacholine. Plasma drug concentrations were measured for each drug over 5 h...

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