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Monoclonal Antibodies

Researchers from Lehigh Valley Hospital report details of new studies and findings in the area of monoclonal antibodies

Published in Drug Law Weekly, November 6th, 2007

Researchers detail in 'Cutaneous adverse reaction to infliximab: report of psoriasis developing in 3 patients,' new data in monoclonal antibodies. According to recent research from the United States, "Infliximab is a chimeric immunoglobulin G1kappa monoclonal antibody against tumor necrosis factor alpha (TNF-alpha), a proinflammatory cytokine that participates in both normal immune function and the pathogenesis of many autoimmune disorders. Treatment with infliximab reduces the biologic activities of TNF-alpha and thus is indicated in the treatment of rheumatoid arthritis, Crohn disease, ankylosing spondylitis, psoriatic arthritis, plaque psoriasis, and ulcerative colitis."

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