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Gastric Cancer Therapy

Study results from Tohoku University, Division of Gastroenterology provide new insights into gastric cancer therapy

Published in Drug Law Weekly, November 13th, 2007

A report, 'Pathophysiological role of the activation of p38 mitogen-activated protein kinases in poorly differentiated gastric cancer,' is newly published data in Pathology International. "p38 mitogen-activated protein kinases (MAPK) contribute to the loss of cell-cell contact and the round cell shape characteristic of poorly differentiated gastric cancer. In the present study it is demonstrated that phospho-p38 MAPK level significantly increased in poorly differentiated gastric cancers in comparison to differentiated cancers and normal gastric mucosa by immunohistochemistry," scientists in Sendai, Japan report.

"Next, the pathophysiological roles of p38 MAPK...

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