Medicinal Chemistry
Findings from Stanford University, Department of Chemistry in medicinal chemistry reported
Published in Drug Law Weekly, November 20th, 2007
"This HLA molecule is involved in the disease pathogenesis by presenting gluten peptides to T cells. Blocking the peptide-binding site of DQ2 may be a way to treat celiac disease. In this study, two types of peptide analogues, modeled after natural gluten antigens, were studied as DQ2 blockers. (a) Cyclic peptides. Cyclic peptides...
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Source: Drug Law Weekly (2007-11-20)
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