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Reports by K.D. Vlugt-Wensink and co-researchers describe recent advances in life sciences

Published in Drug Law Weekly, December 18th, 2007

Fresh data on life sciences are presented in the report 'Preclinical and clinical in vitro in vivo correlation of an hGH dextran microsphere formulation.' In this recently published article, scientists in Leiden, Netherlands conducted a study "To investigate the in vitro in vivo correlation of a sustained release formulation for human growth hormone (hGH) based on hydroxyethyl methacrylated dextran (dex-HEMA) microspheres in Pit-1 deficient Snell dwarf mice and in healthy human volunteers. A hGH-loaded microsphere formulation was developed and tested in Snell dwarf mice (pharmacodynamic study) and in healthy human volunteers (pharmacokinetic study)."

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