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Diabetes Therapy

Data from University of Washington provide new insights into diabetes therapy

Published in Drug Law Weekly, January 1st, 2008

Researchers detail in 'Topical application of laminin-332 to diabetic mouse wounds,' new data in diabetes. "Keratinocyte migration is essential for wound healing and diabetic wound keratinocytes migrate poorly. Keratinocyte migration and anchorage appears to be mediated by laminin-332 (LM-332)," researchers in the United States report.

"Impaired diabetic wound healing may be due to defective LM-332 mediated keratinocyte migration. To evaluate LM-332 expression in diabetic (db/db) and control (db/-) mice and to test LM-332 wound healing effects when applied to mouse wounds. LM-332 expression in mouse wounds was evaluated using immunohistochemistry. LM-332 wound healing...

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